Silagra: A Comprehensive Overview

Published On - 26 Ağustos 2024

doruk 1win India
Characteristic Details
Active Ingredient Sildenafil Citrate
Dosage Forms 50 mg, 100 mg
Route of Administration Oral
Category Phosphodiesterase (PDE5) inhibitor
More on Silagra

Chemical Structure

The active component in Silagra, Sildenafil Citrate, is a crystalline compound. It is structurally a cGMP-specific phosphodiesterase type 5 inhibitor. The molecular formula of Sildenafil Citrate is C22H30N6O4S. The presence of an N-heterocyclic ring confers its ability to interact effectively at the molecular level.

Sildenafil 100 mg is a derivative of piperazine, providing it with the distinct characteristics of its class. The heterocyclic core is integral to its function. Through this complex structure, Sildenafil achieves its pharmacological potency.

Mechanism of Action

Silagra exerts its effect by inhibiting the PDE5 enzyme. This action leads to increased levels of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. Enhanced cGMP levels promote vasodilation and increased blood flow. This process is essential for achieving an erection in response to sexual stimulation.

The systemic effects of Silagra are limited due to its targeted action on PDE5. The mechanism highlights the specificity of Sildenafil 50 mg in treating erectile dysfunction. This targeted approach minimizes systemic side effects while maximizing efficacy.

Warning & Precautions

Careful consideration is required when administering Silagra. Cardiovascular assessment is crucial due to its vasodilatory effects. Use with nitrates can result in severe hypotension. Patients with liver or renal impairment require dosage adjustments.

Potential interactions with alpha-blockers can lead to symptomatic hypotension. Monitoring of hemodynamic parameters is advised. The risk of vision impairment necessitates caution in individuals with retinitis pigmentosa.

Silagra Storage

Silagra should be stored in a cool, dry place away from direct sunlight. Optimal storage conditions maintain the integrity of the Sildenafil 100 mg tablets. Avoid exposure to moisture to prevent degradation of the active ingredient.

Keeping the medication in its original packaging is recommended. This practice ensures protection from environmental factors. Proper storage extends the shelf-life of the product.

Toxicity

Sildenafil overdose can lead to toxicity. Symptoms may include severe hypotension, syncope, and prolonged erection. Immediate medical attention is required in such cases. The therapeutic window is narrow, necessitating adherence to prescribed dosages.

Animal studies reveal minimal carcinogenic potential. The drug’s safety profile is generally favorable. However, hepatotoxicity may occur at high doses, underscoring the importance of dosage regulation.

Silagra for Sale Online

Purchasing Silagra online requires careful source verification. Ensuring the authenticity of the supplier safeguards against counterfeit products. Reliable vendors provide assurance of quality and efficacy.

The accessibility of Silagra 50 mg online offers convenience. Nonetheless, medical consultation remains paramount. Acquiring medication through reputable channels ensures adherence to healthcare standards.

Parameter Value
Molecular Weight 474.6 g/mol
Half-life 3-5 hours
Bioavailability 41%

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